The BR Biochem Probe Sonicator, model BI-650PS, is a versatile laboratory instrument designed for the efficient disruption, homogenization, and emulsification of biological samples using ultrasonic waves. With a power output of 650 watts and a variable frequency range of 20 kHz, this sonicator offers precise control and customization of sonication parameters, making it suitable for a wide range of applications in molecular biology, cell biology, biochemistry, and biotechnology.
At the core of the BI-650PS sonicator is an ultrasonic probe or transducer, which converts electrical energy into high-frequency mechanical vibrations. These vibrations are transmitted to a titanium or stainless steel probe tip, which is immersed in the sample to be processed. The rapid oscillation of the probe generates cavitation bubbles within the sample, leading to the formation of localized high-pressure zones and microstreaming effects that disrupt cell membranes, shear nucleic acids, and homogenize tissue samples.
The BI-650PS sonicator offers precise control over sonication parameters, including power output, frequency, and duration, allowing users to tailor the sonication conditions to their specific experimental requirements. The variable frequency range of 20 kHz enables optimization of sonication efficiency and sample processing for different sample types and volumes. Higher frequencies are typically used for delicate samples or fine particle size reduction, while lower frequencies are more suitable for larger, tougher samples.
The sonicator features a user-friendly interface with intuitive controls for easy programming and operation of sonication protocols. The digital display provides real-time feedback on sonication parameters, such as power output, frequency, and elapsed time, enabling precise monitoring and adjustment of the sonication process. Additionally, the sonicator may offer safety features, such as automatic shutdown in case of overheating or overloading, to protect the instrument and samples from damage.
In summary, the BR Biochem Probe Sonicator BI-650PS offers researchers a powerful and versatile tool for sample processing and manipulation using ultrasonic energy. Its high-power output, variable frequency range, and user-friendly design make it an indispensable instrument for a wide range of applications, including cell lysis, DNA fragmentation, nanoparticle synthesis, emulsification, and dispersion.