LABCARE LB-940 Up-Down: 30 rpm- 2 rpm Disintegration Test Apparatus

The LABCARE LB-940 Up-Down: 30 rpm- 2 rpm Disintegration Test Apparatus is a test apparatus used to determine the disintegration time of tablet dosage forms under specified conditions. The test apparatus is used as an in vitro method to predict drug release rates in vivo. It provides a basic comparative evaluation of the tablet disintegration rate and thus can be used to compare different dosage forms and batches of tablets. It is a device that measures the disintegration time of tablets from the point at which they are placed into the device until no tablet remains. This test is used to determine whether a tablet is suitable for human consumption. It is comprised of a Plexiglass tube fitted with a grinding disk, turned by a motor at 30rpm, to mimic the action of chewing. The grinding disk is coated with the sample of anti-grinding agent and an agitator turns inside the tube to disperse the product as if it were in saliva. The agitator is driven by an electric motor at 2rpm and ensures that there is always agitation within the tube to guarantee that the sample remains dispersed. The result is measured by measuring the time it takes for the sample to break down into its composite components, expressed in milliliters per minute (ml/min).

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